Tight end Vernon Davis #85 of the San Francisco 49ers scores a touchdown against linebacker Bobby Wagner #54 of the Seattle Seahawks in the second quarter on December 8, 2013 at Candlestick Park in San Francisco, California. The 49ers won 19-17. (Photo by Brian Bahr/Getty Images)
Defensive tackle Jesse Williams had to be carted from the practice field on Wednesday after going down during pass rush drills. The team confirmed Williams suffered a knee injury but wouldn't comment further on the nature of the injury.
The injury comes just a day after tight end Anthony McCoy went down in practice with an apparent torn left Achilles tendon.
McCoy missed all of the 2013 season due to a torn right Achilles. Like McCoy, Williams is being haunted by the same injury.
Williams underwent treatment to improve a knee that cause him problems during training camp last year. He ultimately landed on injured reserve and missed the entire season.
Head coach Pete Carroll did not address the matter on Wednesday, so a more definitive update will likely have to wait until Thursday.
Guard James Carpenter (calf) and linebacker Bobby Wagner (hamstring) did not practice after suffering muscle tightness during practice on Tuesday.
Defensive tackle Jimmy Staten (knee/hamstring), tackle Michael Bowie, receiver Paul Richardson (undisclosed) and defensive end O'Brien Schofield (knee) also sat out practice.
Linebacker Kevin Pierre-Louis (oblique) and receiver Kevin Norwood (foot) both returned to practice on Wednesday. However, Norwood was limited and didn't appear to participate in team drills.
Receiver Jermaine Kearse also was out of pads by the end of practice.
Linebackers Bruce Irvin (hip) and Korey Toomer (hamstring) remain on the physically unable to perform list. Cornerback Eric Pinkins (Lisfranc) remains on the non-football injury list.
Linebacker Malcolm Smith (ankle), safety Kam Chancellor (hip) and tackle Russell Okung (foot) remain sidelined after offseason surgeries.
With James Carpenter and Michael Bowie sidelined, the first-team offensive line consisted of Alvin Bailey, Caylin Hauptmann, Max Unger, J.R. Sweezy and Justin Britt.
The second unit consisted of Garry Gilliam, C.J. Davis, Lemuel Jeanpierre, Stephen Schilling and Eric Winston.
With Bobby Wagner out, undrafted rookie Brock Coyle got some run with the first-team defense at middle linebacker. However, he collided with another player and appeared to be briefly shaken up. He was replaced by Heath Farwell with the first-team.
With Anthony McCoy likely done for the year, the battle is wide open for a third tight end behind Zach Miller and Luke Willson.
An interesting possibility is Morrell Presley, an undrafted free agent out of Division II California University (Pa.).
Presley looked impressive at times in one-on-one drills when lined up against safety Terrance Parks.
Presley is battling with Cooper Helfet and RaShaun Allen for a potential third tight end roster spot.